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详细信息
马昆
 

姓名:马昆

办公电话:0427-2631427

电子邮箱:makunonline@163.com

学习和工作经历:

2014.09 –至今     大连理工大学生命与医药学院副教授

2011.03 – 2014.03 美国俄克拉荷马大学化学与生物化学系博士后

2007.09 – 2011.03 浙江大学药学院药剂学博士

2002.09 – 2005.07 新疆医科大学药学院药剂学硕士

1993.09 – 1997.07 新疆医科大学药学院药学学士

研究领域:

1)药物/基因的靶向传递;

2)药物新技术与新剂型;

3)纳米给药系统

代表性论文:

1.Kun Ma, Dong-Dong Wang, Yiyang Lin, et al.Synergetic targeted delivery of sleeping-beauty transposon system to mesenchymal stem cells using LPD nanoparticles modified with phage-displayed targeting peptide.Adv. Funct. Mater.2013;6;23:1172-1181

2.Kun Ma, Minxin Hu, Yan Qi, et al.Structure–transfection activity relationships with glucocorticoid–polyethylenimine conjugate nuclear gene delivery systems.Biomaterials2009;30:3780–3789

3.Kun Ma, Minxin Hu, Yan Qi, et al.PAMAM–Triamcinolone acetonide conjugate as a nucleus–targeting gene carrier for enhanced transfer activity.Biomaterials2009;30:6109–6118

4.Kun Ma, Min-Xin Hu, Meng Xie, et al.Investigation of Polyethylenimine–grafted– Triamcinolone acetonide as Nucleus–Targeting Gene Delivery Systems.J. Gene Med.2010; 12: 669–680

5.Kun Ma, Haijun Shen, Song Shen, Men Xie, Chuanbin Mao, Liyan Qiu, Yi Jin. Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery.J. Gene Med.2011; 13: 290–301.

6. Haijun Shen, Hui Shi,Kun Ma, et al.Polyelectrolyte capsules packaging BSA gels for pH-controlled drug loading and release and their antitumor activity.Acta Biomater. 2013; 9: 6123-6133.

7. Men Xie, Mei Shi,Kun Ma, et al.Hybrid nanoparticles for drug delivery and bioimaging: mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. J. Colloid. Interface Sci. 2013; 395:306-314.

8. Men Xie, Hui Shi, Zhen Li, Haijun Shen,Kun Ma, et al. A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging. Colloids Surf B Biointerfaces. 2013;110C:138-147.

9. Haijun Shen, Hui Shi, Men Xie,Kun Ma, et al.Biodegradable chitosan/alginate BSA-gel-capsules for pH-controlled loading and release of doxorubicin and treatment of pulmonary melanoma. J Mater Chem B 2013;1:32:3906-3917

研究课题

1.“连环”靶向基因载体的研究与应用(国家自然科学基金,面上项目:30873175)

2.基于介孔二氧化硅的门控靶向给药系统的构建及性能评价(国家自然科学基金,面上项目:30973647)

3.新型双分子靶向基因传递系统的研究(浙江省自然科学基金,面上项目:Y2090229)

专利成果

1.金一,马昆,胡敏新,齐岩,王成润;一种糖皮质激素接枝的基因给药载体的制备方法;中国;专利号: ZL200910154930.1

2.金一,马昆,胡敏新,齐岩,王成润;糖皮质激素修饰聚乙烯亚胺的基因载体材料的制备方法;中国;专利号: CN200910154929.1;公开号: CN101864075A;

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